DRUG STABILITY

It is extremely important to preserve the stability of purchased drugs. If the stability of a drug is compromised, it may lead to microbial contamination and degradation. The drug may also broken down into potentially toxic chemicals that may be harmful to the human body.
Factors that can compromise the stability of drugs include:

1. TEMPERATURE: Many drugs are heat sensitive. If stored above a certain temperature, degradation occurs. The drug is then rendered inactive or becomes a medium for microbial contamination. Live inactivated vaccines may revert back to the virulent forms. Hormones also become degraded and inactive.
2. LIGHT: Some drugs are photo labile. This means they become degraded when exposed to light. Such drugs are stored in amber colored containers. They should never be transferred from their original containers to other containers.
3. WATER: Exposure to water compromises the stability of drugs. Water or moisture breaks down such drugs, degrading them and making them prone to microbial contamination. Manufacturers package drugs in moisture proof containers and foils. Many antibiotic syrups are water labile. They are packaged as dry powders and reconstituted prior to administration. They should be used up or discarded within 7 days.