Fish odour syndrome, also known as trimethylaminuria is a metabolic disorder where the body cannot breakdown trimethylamine found in foods like fish and eggs as a result of the deficiency of an enzyme called Flavin containing monooxygenase 3(FMO3). This enzyme breaks down trimethylamine into trimethylamine oxide, an odourless metabolite. An accumulation of trimethylamine in the body leads to its release in sweat, urine, reproductive fluids and breath and the result is a strong fishy odour.
TREATMENT: There is no known treatment for this disorder. People who have avoided foods like fish, eggs, red meat and beans have found significant improvement in their condition.
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